王石峰,2017年毕业于北京中医药大学,医学博士,讲师,生物学和中药学专业。中药系统科学与工程委员会会员。参加国自然重点项目《中药辛/苦味活血化瘀功效的化学和生物学基础研究》。
主要研究兴趣:
1. 中药调节细胞代谢作用。
2. 高通量高内涵药物筛选。
代表性论文:
1. Jiayu Zhang#1, Shifeng Wang#1, Lulu Xu, Qiao Zhang, Zhanpeng Shang, Yanling Zhang, Qinghua Wu, Shiyou Li*, Yanjing Qiao*. Multiple Perspectives of Qingkailing Injection-Fraction-Single Compound in Revealing the Hepatotoxicity of Baicalin and Hyodeoxycholic Acid, J Ethnopharmacol, 2018,215:147-155. (Co-first authors)
2. Shifeng Wang, Yuxin Zhang, Qiao Zhang, Sha Peng, Cheng Shen, Yangyang Yu, Minyu Zhang, Wei Yang, Qinghua Wu, Yanling Zhang, Shiyou Li*, Yanjiang Qiao*. Content decline of SERCA inhibitors saikosaponin a and d attenuates cardiotoxicity and hepatotoxicity of vinegar-baked Radix Bupleuri. Environ Toxicol Phar, 2017, 52:129-137.
3. Yuxin Zhang, Xing Wang, Xi Li, Sha Peng, Shifeng Wang, Christopher Z. Huang, Corine Z. Huang, Qiao Zhang, Dai Li, Jun Jiang, Qin Ouyang, Yanling Zhang, Shiyou Li*, Yanjiang Qiao*. Identification of a specific agonist of human TAS2R14 from Radix Bupleuri through virtual screening, functional evaluation and binding studies. Sci Rep, 2017;7: 12174.
4. Xiaona Liu, Shifeng Wang, Zhisheng Wu, Zhaoyi Wang, Yanjiang Qiao*. Scientific fusion of liver-based therapy of traditional Chinese medicine theory and modern deoxyschizandrin nano-delivery system on the hepatoprotective activity. 2017, J Control Releas (Abstract).
5. Minyu Zhang, Feifei Guo, Hongwei Yang, Yangyang Yu, Junying Wei, Shifeng Wang, et al. DanHong injection targets endothelin receptor type B and angiotensin II receptor type 1 in protection against cardiac hypertrophy. Oncotarget, October 2017.
6. Minyu Zhang, Hongwei Wu, Feifei Guo, Yangyang Yu, Junying Wei, Ya Geng, Shifeng Wang, Shiyou Li*, Hongjun Yang*. Identification of active components in Yixinshu Capsule with protective effects against myocardial dysfunction on human induced pluripotent stem cell-derived cardiomyocytes by an integrative approach. Mol Biosyst, 2017, 13(8):1469-1480.
7. Shifeng Wang, Qiao Zhang, Yuxin Zhang, Cheng Shen, Zhen Wang, Qinghua Wu, Yanling Zhang, Shiyou Li*, Yanjiang Qiao*. Agrimol B suppresses adipogenesis through modulation of SIRT1-PPARγ signal pathway. Biochem Bioph Res Co, 2016,477(3):454-460.
8. Shifeng Wang, Chenxi Zhai, Yuxin Zhang, et al. Cardamonin, a novel antagonist of hTRPA1 cation channel, reveals therapeutic mechanism of pathological pain. Molecules, 2016,21(9).pii:E1145.
9. Shifeng Wang, Qiao Zhang, Yuxin Zhang, Yanling Zhang, Qinghua Wu, Shiyou Li*, Yanjiang Qiao*. Identification of berbamine dihydrochloride from barberry as an anti-adipogenic agent by high-content imaging assay. Journal of Traditional Chinese Medical Sciences, 2016,3:91-99.
10. Qiao Zhang, Shifeng Wang, Yangyang Yu, Shengnan Sun, Yuxin Zhang, Yanling Zhang, Wei Yang, Shiyou Li*, Yanjiang Qiao*. Salvianolic Acid A, as a novel ETA receptor antagonist, shows inhibitory effects on tumor in vitro. Int J Mol Sci, 2016, 17(8): pii:E1244.
11. Yangyang Yu, Shengnan Sun, Shifeng Wang, Qiao Zhang, Ming Li, Feng Lan, Shiyou Li*, Chunsheng Liu*. Liensinine- and neferine-induced cardiotoxicity in primary neonatal rat cardiomyocytes and human-induced pluripotent stem cell-derived cardiomyocytes. Int J Mol Sci, 2016, 17(2). pii:E186.
大会报告:
2017年11月:世界中医药学会联合会信息专业委员会第七届学术年会青年论坛(浙江嘉兴)
主题:“智慧中医服务人类健康学术交流会”
报告题目:《中药五味药性研究对新药发现的启示》
联系方式:
通讯地址:北京市房山区阳光南大街北京中医药大学中药学院C座406
邮政编码:102488
E-mail: wangshifeng@bucm.edu.cn